Nonobstructive Coronary Artery Disease and Risk of Myocardial Infarction

ICAM-1 Polymorphisms (G241R, K469E), in Coronary Artery Disease and Myocardial Infarction

Background: Inflammation plays a critical role in atherogenesis. The initial step in atherosclerosis is the adhesion of leukocytes to activated endothelial cells mediated by ICAM-1, an inflammatory protein. Several polymorphisms for Intracellular adhesion molecule -1(ICAM-) gene have been described. Objective: To determine the possible role of G241R and K469E polymorphisms in development of cor...

Integrin Beta-3 Gene Polymorphism and Risk for Myocardial Infarction in Premature Coronary Disease

Background: Contradictory results have been obtained regarding the role of integrin, beta 3 (ITGB3) gene polymorphisms in occurrence of myocardial infarction (MI). Objectives: We aimed to assess the association between 1565C/T polymorphism of ITGB3 gene and increased risk for acute MI in patients with premature coronary artery disease (CAD). <strong...

c1019t polymorphism in the connexin 37 gene and myocardial infarction risk in premature coronary artery disease

background: the c1019t polymorphism of the connexin-37 (gja4) gene is a single-nucleotide polymorphisms involved in atherosclerotic plaque rupture and atherosclerosis predisposition. we examined the association between the c1019t polymorphism of the gja4 gene and the occurrence of myocardial infarction (mi) in patients with premature coronary artery disease (cad). methods: our study recruited 1...

Anthropometric Measures and the Risk of Coronary Artery Disease

Nonobstructive Coronary Artery Disease by Coronary CT Angiography Improves Risk Stratification and Allocation of Statin Therapy.

OBJECTIVES This study sought to determine prognostic value of nonobstructive coronary artery disease (CAD) for atherosclerotic cardiovascular disease (ASCVD) events and to determine whether incorporation of this information into the pooled cohort equation reclassifies recommendations for statin therapy as defined by the 2013 guidelines for cholesterol management of the American College of Cardi...